When it comes to comfort food with a bold twist, Cajun Chicken Rollups with Roasted Red Pepper Cream Sauce strike the perfect balance between spicy, cheesy, and creamy. This crowd-pleasing dish is a restaurant-quality recipe you can make easily at home, combining tender chicken, gooey cheese, and a rich, flavorful sauce that’s simply unforgettable.

In this detailed article, we’ll walk through every aspect of preparing Cajun Chicken Rollups—from pounding and seasoning the chicken to whipping up the decadent roasted red pepper cream sauce. Whether you’re looking to spice up your weeknight dinners or impress guests at a dinner party, this recipe is a winner.

Why You’ll Love These Cajun Chicken Rollups

These Cajun Chicken Rollups are:

Bursting with Flavor: A perfect blend of spicy Cajun seasoning and melted cheese.
Elegant Yet Easy: They look fancy but are straightforward enough for weeknight cooking.
Customizable: You can adjust the heat level or use different cheeses if preferred.
Rich and Creamy: The roasted red pepper cream sauce is luscious, tangy, and comforting.

Ingredients You’ll Need

For the Cajun Chicken Rollups

4 boneless, skinless chicken breasts (pounded thin for easier rolling)
1½ teaspoons Cajun seasoning (plus more to taste)
1 teaspoon garlic powder
Salt and pepper, to taste
1 cup shredded mozzarella cheese
½ cup shredded pepper jack cheese
2 tablespoons olive oil

For the Roasted Red Pepper Cream Sauce

1 tablespoon butter
2 cloves garlic, minced
½ cup jarred roasted red peppers, finely chopped
1 cup heavy cream
½ teaspoon Cajun seasoning
¼ cup grated Parmesan cheese
Salt and pepper, to taste

Optional Garnish

Fresh chopped parsley
Extra Parmesan

Kitchen Tools You’ll Need

Sharp knife and cutting board
Meat mallet or rolling pin (to pound chicken)
Skillet or sauté pan
Small saucepan
Measuring spoons and cups
Toothpicks or kitchen twine (to secure rollups)

Cajun Chicken Rollups with Roasted Red Pepper Cream Sauce

How to Make Cajun Chicken Rollups Step-by-Step

Step 1: Prepare the Chicken

Pound the chicken breasts: Place each breast between two pieces of plastic wrap and pound them to about ¼ inch thickness. This ensures even cooking and makes rolling easier.
Season the chicken: Sprinkle both sides of each chicken breast with Cajun seasoning, garlic powder, salt, and pepper. Don’t be shy with the seasoning—it’s what gives the dish its signature flavor.

Step 2: Add the Cheese Filling

Layer the cheeses: In a bowl, mix the shredded mozzarella and pepper jack cheese. Sprinkle an even layer of the cheese mixture over each piece of seasoned chicken.
Roll tightly: Starting at one end, roll each chicken breast tightly. Secure with toothpicks or kitchen twine if needed to hold the shape during cooking.

Step 3: Cook the Chicken Rollups

Heat the olive oil: In a large skillet over medium heat, add the olive oil.
Sear the rollups: Add the chicken rollups seam side down. Sear each side for about 3–4 minutes or until golden brown.
Finish cooking: Cover the pan and cook on low heat for another 5–10 minutes, or until the internal temperature reaches 165°F (74°C).

How to Make the Roasted Red Pepper Cream Sauce

Step 1: Sauté Garlic and Peppers

In a small saucepan, melt butter over medium heat.
Add minced garlic and sauté until fragrant, about 1 minute.
Stir in the chopped roasted red peppers and cook for 2 more minutes.

Step 2: Add Cream and Seasoning

Pour in the heavy cream and stir to combine.
Add Cajun seasoning and Parmesan cheese.
Simmer for 4–5 minutes, stirring occasionally, until the sauce thickens.
Season with salt and pepper to taste.

Step 3: Blend (Optional)

For a smoother sauce, you can blend the mixture using an immersion blender or standard blender until creamy. This step is optional, depending on your texture preference.

Serve and Garnish

Plate the chicken rollups and spoon the roasted red pepper cream sauce generously over the top.
Garnish with chopped parsley and extra Parmesan for a pop of color and added flavor.
Serve with sides like garlic mashed potatoes, sautéed green beans, or roasted vegetables.

Tips for Success

Pound evenly: Uniform thickness ensures the chicken cooks at the same rate.
Don’t overstuff: Too much cheese can cause the rollups to burst while cooking.
Let them rest: After cooking, let the chicken rest a few minutes to retain juices.
Make ahead: You can prep the rollups in advance and refrigerate until ready to cook.

Variations and Substitutions

Cheese: Substitute provolone, gouda, or cheddar for a different flavor profile.
Protein: Try with turkey cutlets or thin pork chops instead of chicken.
Sauce: Swap the red pepper cream sauce for Alfredo or pesto if desired.
Spice level: Add crushed red pepper flakes or hot sauce for extra heat.

Nutritional Overview (per serving)

Note: Based on approximate values for 4 servings.

Calories: 480–550 kcal
Protein: 35g
Fat: 34g
Carbohydrates: 6–8g
Sugar: 2g
Fiber: 1g
Sodium: 600–800mg

This dish is high in protein and fat, making it satisfying and indulgent. You can reduce calories by using light cream or less cheese if desired.

Frequently Asked Questions (FAQs)

Can I make this dish ahead of time?

Yes! Assemble the rollups, cover, and refrigerate for up to 24 hours. Cook just before serving for best results.

Can I freeze Cajun Chicken Rollups?

Absolutely. Wrap each cooked or uncooked rollup tightly in plastic wrap and foil. Freeze for up to 2 months. Thaw overnight in the refrigerator before cooking or reheating.

What sides go best with this dish?

Try pairing it with:

Steamed or roasted vegetables
Mashed potatoes or cauliflower mash
Rice pilaf
Garlic bread or dinner rolls

Can I make the sauce spicier?

Yes, feel free to add extra Cajun seasoning or a splash of hot sauce for more heat.

Storage and Reheating

To Store:

Place leftovers in an airtight container.
Refrigerate for up to 3 days.

To Reheat:

Microwave in 30-second intervals until heated through.
Or reheat gently on the stovetop with a splash of cream to keep the sauce smooth.

Perfect for Any Occasion

These Cajun Chicken Rollups are versatile enough for:

Family dinners: Kid-friendly and satisfying.
Date nights: Impressive presentation with minimal fuss.
Dinner parties: Elegant yet easy to serve.
Meal prep: Make ahead and reheat when needed.

Final Thoughts

Cajun Chicken Rollups with Roasted Red Pepper Cream Sauce offer a perfect combination of spice, comfort, and sophistication. The Cajun spices wake up your palate, while the creamy sauce balances it out with rich, velvety goodness. It’s a dish that will have everyone asking for seconds.

Whether you’re new to cooking or a seasoned chef, this recipe delivers big flavor without complicated steps. With its restaurant-quality taste and stunning appearance, it’s sure to become a staple in your meal rotation.

Try This Recipe Tonight!

Ready to elevate your dinner game? Give these Cajun Chicken Rollups a try. Once you do, they’ll be a regular request from family and guests alike. Don’t forget to top it with that creamy roasted red pepper sauce—it’s the real star of the show.